What is Cozaar and why is it prescribed?

Cozaar (Losartan) is used in the treatment of high blood pressure. Cozaar is effective when used alone or with other high blood pressure medications, such as diuretics that help the body get rid of water.

Cozaar is also used to slow the progress of kidney disease caused by type 2 diabetes (the type of diabetes that does not require insulin shots). It is the first of a new class of blood pressure medications called angiotensin II receptor antagonists. Cozaar works, in part, by preventing the hormone angiotensin II from constricting the blood vessels, which tends to raise blood pressure.

How does Cozaar work?

Cozaar (losartan) and its primary metabolite block the angiotensin receptor found in many tissues, primarily in vascular smooth muscle. Angiotensin, formed by the action of angiotensin converting enzyme (ACE), is a powerful chemical that causes blood vessel narrowing (vasoconstriction) which can lead to elevated blood pressure (hypertension).

Special warnings about Cozaar: Cozaar can cause low blood pressure, especially if you are also taking a diuretic. You may feel light-headed or faint, especially during the first few days of therapy. If these symptoms occur, contact your doctor. Your dosage may need to be adjusted or discontinued. Be sure you know how you react to Cozaar before you drive or operate machinery.

Excessive sweating, dehydration, severe diarrhea, or vomiting could make you lose too much water, causing a severe drop in blood pressure. Call your doctor if you experience any of these symptoms.

Be sure to tell your doctor about any medical conditions you have, especially liver or kidney disease and congestive heart failure. In very rare cases, Cozaar has triggered fatal kidney problems in people with heart failure.

Cozaar tends to increase the level of potassium in the blood. Check with your doctor before taking potassium supplements or using a salt substitute.

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