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Cozaar (losartan) and its primary metabolite block the angiotensin receptor found in many tissues, primarily in vascular smooth muscle. Angiotensin, formed by the action of angiotensin converting enzyme (ACE), is a powerful chemical that causes blood vessel narrowing (vasoconstriction) which can lead to elevated blood pressure (hypertension). More...
Special information on Cozaar Excessive sweating, dehydration, severe diarrhea, or vomiting could make you lose too much water, causing a severe drop in blood pressure. Call your doctor if you experience any of these symptoms. Be sure to tell your doctor about any medical conditions you have, especially liver or kidney disease and congestive heart failure. In very rare cases, Cozaar has triggered fatal kidney problems in people with heart failure. More...
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